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Dr Geraldine Bastien

Dr Geraldine BastienOVERVIEW

I carried out my MSc in Molecular and Cell Biology at Ecole Normale Supérieure (Lyon, France) where I acquired research experience in the field of plant biochemistry, at Max-Planck-Institute for Molecular Plant Physiology (Potsdam, Germany) and in the molecular mechanisms of plant-bacteria symbioses at the Research Institute for Development (Montpellier, France). During my PhD thesis at the French National Institute for Agricultural Research (Toulouse, France), I set up a functional metagenomic approach and used next generation sequencing and protein biochemistry to characterize the diversity of Carbohydrate-Active Enzymes encoded by the gut microbiota of tropical wood-feeding termites.

Since July 2013, I have been working with Dr. Sarah Perkins examining how gut bacteria (microbiota) interact with parasitic helminths (macrobiota), based in the laboratories at the Department of Biodiversity and Molecular Ecology of the Foundation Edmund Mach (San Michele, Italy), and in collaboration with the School of Biosciences at Cardiff University (Cardiff, UK).

CONTACT

Position:   Post-doctoral researcher

Email: geraldineliliane.bastien@fmach.it

Telephone:  +39 0461 615 571

Location: Biodiversity and Molecular Ecology Department, Research and Innovation Centre, Foundation Edmund Mach, Via Mach, 1, 38010 S. Michele all’Adige, (TN), Italy

 

RESEARCH

My present research interests focus on:

  • Analysis of 16S DNA diversity using Next Generation Sequencing
  • Modulation of the gut microbiota by parasitic helminths
  • Co-infection patterns in wild-rodents
  • Wildlife diseases and pathogen transmission by nematodes

 

PUBLICATIONS

Bastien G., Arnal G., Bouchez O., Henrissat B., Ferreira F., Fauré R., Laguerre S., Lefèvre F., Robe P., Noirot C., Bozonnet S., Dumon C., O’Donohue M.J. (2013). Mining for hemicellulases in the fungus-growing termite Pseudacanthotermes militaris using functional metagenomics. Biotechnology for biofuels 14;6(1):78. doi:10.1186/1754-6834-6-78

Bonaldi K., Gherbi H., Franche C., Bastien G., Fardoux J., Barker D., Giraud E., Cartieaux F. (2010). Development of genetic tools for a first functional study in Aeschynomene indica: spatio-temporal expression of the MtENOD11 early nodulin gene promoter during the Nod-independent symbiosis. Molecular Plant-Microbe Interaction 23(12):1537-44. doi:10.1094 / MPMI -06-10-0137

Patents

Dumon C., Bastien G., Henrissat B., Arnal G., Laguerre S., Bozonnet S., O’Donohue M.J. (2013). Hemicellulase ayant une activité Bêta-D-xylosidase et une activité acétyle xylane estérase. Patent Application.

Communications in international conferences

Bastien G., Kreisinger, J., Pascoe E., Hauffe H.C., Perkins S.E. Composition of the gut microbiota of the yellow-necked mouse, Apodemus flavicollis. Spring Meeting of the British Society for Parasitology, Cambridge, UK, 6th -9th April 2014.

Bastien G., Kreisinger, J., Pascoe E., Hauffe H.C., Perkins S.E. Composition of the gut microbiota of the yellow-necked mouse, Apodemus flavicollis. 1st European Meeting for Young Researchers on soil-transmitted Helminths, Jongny, Switzerland, 23rd-26th March 2014.

Bastien G., Arnal G., Bouchez O., Henrissat B., Ferreira F., Fauré R., Laguerre S., Lefèvre F., Robe P., Noirot C., Bozonnet S., Dumon C., O’Donohue M.J. Mining for hemicellulases in termites using functional metagenomics. 10th Carbohydrate Bioengineering Meeting, Prague, Czech Republic, 21st -24th April 2013.

Bastien G., Bozonnet S., Ferreira F., Fauré R., Robe P., Lefèvre F., Gaspin C., Dumon C., O’Donohue M.J. Functional metagenomics for discovery of new Lignocellulose-acting enzymes. Gut Microbiology Conference, Edinburgh, UK, 2011.

Bastien G., Bozonnet S., Ferreira F., Fauré R., Robe P., Lefèvre F., Gaspin C., Dumon C., O’Donohue M.J. Functional metagenomics for discovery of new Carbohydrate-modifying-enzymes. Gordon Conference of Applied and Environmental Microbiology, South Hadley, MA, USA, 2009.